Insulin Resistance and the Web of Metabolic Chaos

Insulin Resistance and the Web of Metabolic Chaos reframes insulin resistance as far more than a pre-diabetes waypoint—it is a whole-body signaling disorder that drives blood sugar dysregulation, chronic inflammation, lipid remodeling, hormone disruption, and escalating cardiac stress long before glucose or A1c waves a red flag. In this clinically grounded, functional-medicine–focused lecture, providers will learn to recognize the early physiologic fingerprints of insulin resistance across multiple tissues (liver, muscle, adipose, brain, and vascular endothelium), understand the downstream “domino effects” on triglycerides/HDL patterns, androgen and cortisol balance, inflammatory cascades, and sympathetic/cardiometabolic strain, and translate these insights into practical, stepwise care. We will walk through comprehensive lab interpretation—including fasting insulin/glucose, HOMA-IR, QUICKI, insulin-to-glucose ratios, postprandial patterns, and advanced cardiometabolic markers—so clinicians can detect risk earlier, stratify severity, and track response. The session integrates real-world intervention strategies using diet, targeted supplements, lifestyle therapeutics, and judicious medication use, offering clear clinical pathways to reverse or substantially improve insulin resistance and reduce long-term disease burden.